Bulletin of Experimental Biology and Medicine

, Volume 79, Issue 3, pp 253–254 | Cite as

Dynamics of the content and synthesis of nucleic acids and proteins in the lungs during adaptation to hypoxia

  • A. F. Bogomolov
Pathological Physiology and General Pathology
  • 10 Downloads

Abstract

The relative weight of the lungs and the synthesis of nucleic acids and protein in the lungs of rats adapted to hypoxia were studied. Adaptation was carried out for 6 h a day in a pressure chamber at an “altitude” of 7000 m for 40 days. An increase in the relative weight of the lungs, in the relative (per 100 mg lung tissue) and total RNA content, and in the intensity of protein synthesis was found. The relative DNA content (per 100 mg) in the lung tissue was unchanged.

Key Words

hypoxia lungs synthesis of nucleic acids and protein 

Literature Cited

  1. 1.
    P. V. Vasil'ev, V. B. Malkin, V. F. Babchinskii, et al., in: Problems in Space Biology [in Russian], Vol. 8, Moscow (1968), p. 122.Google Scholar
  2. 2.
    A. P. Davydov, in: Current Problems in the Biochemistry of Respiration and Clinical Medicine [in Russian], Vol. 2, Ivanovo (1972), p. 135.Google Scholar
  3. 3.
    F. Z. Meerson, M. Ya. Maizelis, and V. B. Malkin, Izvest. Akad. Nauk SSSR, Ser. Biol., No. 6, 819 (1969).Google Scholar
  4. 4.
    A. S. Spiring, Biokhimiya, No. 5, 656 (1958).Google Scholar
  5. 5.
    G. Schmidt and S. J. Thannhauser, J. Biol. Chem.,161, 183 (1945).Google Scholar
  6. 6.
    H. Sobel and F. M. Cohen, Proc. Soc. Exp. Biol. (New York),99, 656 (1958).Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • A. F. Bogomolov

There are no affiliations available

Personalised recommendations