Bulletin of Experimental Biology and Medicine

, Volume 78, Issue 2, pp 943–945 | Cite as

Effect of thyrocalcitonin on the mineral component of regenerating bone during healing of fractures

  • V. A. Landa
  • A. I. Briskin
Experimental Biology


Changes in the state of the mineral component of bone tissue (hydroxyapatite) during reparative regeneration of bone after administration of thyrocalcitonin (TCT) were studied in experiments on rabbits. Methods of histology, quantitative microroentgenography, and x-ray diffraction were used. TCT has no marked stimulant effect on normal osteogenesis and mineralization of newly formed bone tissue. However, mineralization of the callus follows an optimal course and osteoporosis of the fragments is much less marked than in animals not receiving TCT.

Key Words

regeneration of bone thyrocalcitonin mineralization of bone tissue hydroxyapatite 


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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • V. A. Landa
  • A. I. Briskin

There are no affiliations available

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