Abstract
The effect of adrenalin, acetylcholine, histamine, thrombin, heparin, fibrinogen, and ADP on the electrokinetic potential of human and canine erythrocytes was studied. Heparin increases the ζ-potential and the other substances reduce it. The mechanisms of action of these substances on the electrokinetic properties of the erythrocyte membrane are discussed.
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Literature Cited
I. Ya. Ashkinazi, Buyll. Éksperim. Biol. i Med., No. 7, 45 (1966).
A. D. Naumov, in: The Blood Clotting System and Fibrinolysis [in Russian], Kiev (1969), p. 119.
A. L. Chizhevskii, Structural Analysis of Moving Blood [in Russian], Moscow (1959).
H. A. Abramson, Electrokinetic Phenomena and Their Application to Biology and Medicine, New York (1934).
H. A. Abramson, L. S. Moyer, and M. H. Gorin, Electrophoresis of Proteins and the Chemistry of Cell Surfaces, Hafner, New York (1942).
J. Burell, J. I. Gardner, and R. O. Frield, Science,165, 862 (1969).
A. S. G. Curtis, The Cell Surface: Its Molecular Role in Morphogenesis, Academic Press (1967).
D. A. Haydon and G. V. F. Seaman, Arch. Biochem.,122, 126 (1967).
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Rusyaev, V.F., Savushkin, A.V. Effect of biologically active substances on the electrokinetic properties of erythrocytes. Bull Exp Biol Med 78, 862–864 (1974). https://doi.org/10.1007/BF00803909
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DOI: https://doi.org/10.1007/BF00803909