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The effect of extracts of hippophae rhamnoides upon the development of tumor transplants in animals

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The antitumor activity of alcohol extracts of the bark ofHippophae rhamnoides as well as the bark of the tree itself was tested upon 10 different forms of transplantable tumors found in mice and rats.

Tumors were markedly inhibited in 8 of the 10 types of tumor tested even if complete resorption failed to be observed.

The preparation is still very crude and toxic. More studies of the active ingredients are needed before the material will be suitable for clinical trial.

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Literature Cited

  1. E. Ch. Pukhalskaia, M. F. Petrova and P. S. Massagetov, Biull. Eksptl. Biol. i Med. XLIV, No. 6, 57–60, 1957. Original Russian pagination. See G. B. Translation.

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Authors and Affiliations

  1. Laboratory of Experimental Chemotherapy of the Institute of Experimental Pathology and Therapy of Cancer, Acad. Med. Sci. USSR, Moscow

    E. Ch. Pukhalskaia

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  1. E. Ch. Pukhalskaia
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Pukhalskaia, E.C. The effect of extracts of hippophae rhamnoides upon the development of tumor transplants in animals. Bull Exp Biol Med 45, 363–366 (1958). https://doi.org/10.1007/BF00803349

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  • DOI: https://doi.org/10.1007/BF00803349

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