European Journal of Nuclear Medicine

, Volume 9, Issue 6, pp 272–277 | Cite as

PET tomography in studies of distributions of 7.6-min potassium 38 in the dog heart

  • William G. Myers
  • Rodney E. Bigler
  • Martin C. Graham


Potassium 38 emits a 2.68-MeV (max) positron, followed promptly by a 2.17-MeV γ-ray in 99.8% of its disintegrations. A positron is emitted also, followed by a 3.94-MeV γ-ray, in 0.2% of the decays. The pairs of 511-keV PET±γ-quanta, which are emitted at 180±0.3° to each other, are in true coincidence with the prompt γ-rays emitted by the daughter nucleus, within the resolving time of PET instrumentation. Studies made with phantoms by means of a commercial version of the MGH PET camera demonstrated that quantitatively satisfactory images are derived, despite the presence of the prompt γ-rays. Two-dimensional (2-D) focal-plane images reveal high uptake of38K promptly in the myocardium of dogs, under barbiturate sedation. Third-dimensional (3-D) transverse section PET tomographic images, through four 1.0-cm-thick heart “slices” orthogonal to the plane of the 2-D images and with 1.4-cm sequential spacing, show38K uptake to be concentrated especially highly in the left ventricle, as expected. Peak levels of activity were observed over the myocardium at 12 s after intravenous bolus injection of ionic38K. Dynamic mode 2-D images were taken at intervals as short as 0.5 s and extending to 1 h.


Left Ventricle Transverse Section Barbiturate Bolus Injection Sequential Spacing 


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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • William G. Myers
    • 1
    • 3
    • 2
  • Rodney E. Bigler
    • 1
    • 2
  • Martin C. Graham
    • 1
    • 2
  1. 1.Graduate School of Medical SciencesMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Graduate School of Medical SciencesCornell UniversityNew YorkUSA
  3. 3.Department of RadiologyThe Ohio State UniversityColumbusUSA

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