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Age differences in temperature dependence of repolarization of the adrenocortical cell membrane

  • Physiology
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Abstract

In experiments on isolated adrenals of male rats of two age groups (5 and 28–29 months) no age differences were found in the membrane potential of cells in the zona fasciculata of the cortex. The temperature dependence of repolarization of the cell membrane in the zona fasciculata of the adrenal cortex was investigated in rats of different ages within the temperature range from 7 to 17°C after preliminary cooling of the adrenals. The temperature coefficient of repolarization, calculated in old animals (Q10=2.732) was significantly higher than in the young animals (Q10=1.481). With age, the contribution of reactions with high activation energy increases in total balance of processes determining repolarization of the adrenocortical cell membrane.

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Gorban', E.N. Age differences in temperature dependence of repolarization of the adrenocortical cell membrane. Bull Exp Biol Med 86, 1572–1574 (1978). https://doi.org/10.1007/BF00801804

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  • DOI: https://doi.org/10.1007/BF00801804

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