Bulletin of Experimental Biology and Medicine

, Volume 87, Issue 3, pp 211–214 | Cite as

Binding of prostaglandins E by plasma membranes of thyroid cells

  • V. D. Malinkovich
  • V. Yu. Gal'chinskaya
Biochemistry and Biophysics


The ability of the plasma membranes of human and bovine thyrocytes to bind prostaglandins of the E group (PGE) was investigated by the use of material from kits for the radioimmunological determination of PGE. Sites for specific binding of PGE with high and low affinity constants for prostaglandins were found to exist on the plasma membranes of human and bovine thyrocytes. Binding of PGE by the membrane is under the influence of thyrotrophin and cyclic nucleotides.

Key Words

prostaglandins plasma membrane thyroid gland cyclic nucleotides 


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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • V. D. Malinkovich
  • V. Yu. Gal'chinskaya

There are no affiliations available

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