Bulletin of Experimental Biology and Medicine

, Volume 85, Issue 1, pp 86–88 | Cite as

Effect of erythrocytic G2-chalone on the kinetics of erythropoiesis in mice

  • G. V. Neustroev
Experimental Biology


Erythrocytic inhibitor (G2-chalone) was shown to act on both proliferating and differentiating cells of the erythroid series in mouse bone marrow. The effect of the chalone was observed as early as 3 h after injection and continued for 8 to 48 h thereafter depending on the degree of cell differentiation. After a single injection of chalone, despite considerable disturbances of erythropoiesis, the number of erythrocytes counted after 8–12 days remained within the control limits. After repeated injections of the chalone the erythrocyte count fell in the late stages of the experiment.

Key Words

erythrocytic inhibitor G2-chalone bone marrow cells 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • G. V. Neustroev

There are no affiliations available

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