Bulletin of Experimental Biology and Medicine

, Volume 85, Issue 1, pp 32–34 | Cite as

Effect of hyperoxia on content of the polyamines spermine and spermidine in rat brain and liver

  • E. Z. Tsvetnenko
  • V. S. Shugalei
Biochemistry and Biophysics


The effect of an increase in the oxygen pressure (6 atm) on the content of the polyamines spermine and spermidine in the rat brain and liver was investigated. During the period of oxygen convulsions and 4 h after decompression the spermidine concentration in the brain and liver was reduced. The spermine concentration in the brain also was reduced during the period of convulsions, but 4 h after decompression it was significantly increased, although, still below the control level. The spermine level in the liver was unchanged during oxygen convulsions, but rose sharply during the next 4 h. The role of polyamines in the regulation of protein biosynthesis during hyperoxia is discussed.

Key Words

hyperoxia spermine spermidine 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • E. Z. Tsvetnenko
  • V. S. Shugalei

There are no affiliations available

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