Effect of hyperoxia and the protective action of urea on serum hemoglobin, transferrin, and total iron concentrations

  • V. V. Vnukov
  • A. A. Krichevskaya
  • A. I. Lukash
Pathological Physiology and General Pathology


During exposure of albino rats to oxygen under a pressure of 4 atm for 1 h (the preconvulsive state) and of 6 atm (convulsive state) an increase in the serum hemoglobin concentration was found. The total ion concentration increased at the same time. By disc electrophoresis in 7.5% polyacrylamide gel, changes in the ratio between the hemoglobin fractions in the serum were found in both stages of oxygen poisoning. An increase in the concentration of transferrins was found during hyperoxia under these conditions. If urea was administered to the animals before the session of hyperbaric oxygenation, the changes observed were less marked.

Key Words

hyperoxia blood serum hemoglobin total iron transferrins 


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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • V. V. Vnukov
  • A. A. Krichevskaya
  • A. I. Lukash

There are no affiliations available

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