Abstract
A decrease in the biological activity of epidermal G2-chalone, isolated from the dorsal skin of rats, was demonstrated 1–2 days after treatment with the carcinogen methylnitrosourea and one day after epilation. The results of quantitative analysis of mitoses and morphological analysis of the skin which was the source of the chalones showed that this effect is based on different mechanisms.
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Ketlinskii, S.A., Okulov, V.B. Changes in epidermal chalone activity during response of the skin to application of carcinogen and epilation. Bull Exp Biol Med 85, 381–383 (1978). https://doi.org/10.1007/BF00801365
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DOI: https://doi.org/10.1007/BF00801365