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Serotonin metabolism in duodenal tissue of intact rabbits

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The concentrations of serotonin and 5-hydroxyindoleacetic acid and monoamine oxidase activity in the duodenal tissue of rabbits are significantly higher than in the kidney. This reflects the greater ability of the intestine to accumulate serotonin and to carry out its catabolism. The opposite relationship was found for 5-hydroxytryptophan decarboxylase, the activity of which was about 12 times higher in the kidney than in the duodenum; this evidently reflects the low ability of the tissue to decarboxylate 5-hydroxytryptophan.

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Authors
  1. M. V. Ermolaev
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  2. M. V. Semenova
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Ermolaev, M.V., Semenova, M.V. Serotonin metabolism in duodenal tissue of intact rabbits. Bull Exp Biol Med 85, 309–310 (1978). https://doi.org/10.1007/BF00801343

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  • DOI: https://doi.org/10.1007/BF00801343

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