Bulletin of Experimental Biology and Medicine

, Volume 85, Issue 3, pp 304–305 | Cite as

Changes in the fatty acid composition of lipids in the blood plasma and certain organs in traumatic shock

  • V. E. Nikolaev
Biochemistry and Biophysics


The fatty acid composition of the total lipids of the myocardium, lungs, liver, intestine, adipose tissue, and blood plasma was investigated in the course of development of traumatic shock produced in dogs by crushing the soft tissues of the thigh. The development of shock is accompanied by an increase in the relative percentage of linoleic and arachidonic acids in the blood plasma and certain organs; close correlation was found between the linoleic acid concentrations in the adipose tissue and blood. A deficiency of oleic acid also was observed in the lipids of the organs studied.

Key Word

traumatic shock fatty acids 

Literature Cited

  1. 1.
    M. L. Mikhailov, Kardiologiya, No. 1, 88 (1972).Google Scholar
  2. 2.
    M. Cohen, J. Sztokalo, et al., Life Sci.,13, 317 (1973).Google Scholar
  3. 3.
    A. G. Coran, P. E. Cryer, D. L. Horwitz, et al., Surgery,71, 465 (1972).Google Scholar
  4. 4.
    J. Folch et al., J. Biol. Chem.,226, 497 (1957).Google Scholar
  5. 5.
    Y. Goto, Jpn. Circulat. J. (English edition),26, 121 (1962).Google Scholar
  6. 6.
    D. E. Heath and H. B. Stoner, Br. J. Exp. Pathol.,49, 160 (1968).Google Scholar
  7. 7.
    H. Laborit et al., Chemico-Biol. Interact.,10, 239 (1975).Google Scholar
  8. 8.
    L. Opie, Nature,227, 1055 (1970).Google Scholar
  9. 9.
    J. Rose, M. Johnson, P. Ramwell, et al., Proc. Soc. Exp. Biol. (New York),147, 652 (1974).Google Scholar
  10. 10.
    J. Spitzer and J. Spitzer, Am. J. Physiol.,222, 101 (1972).Google Scholar
  11. 11.
    P. Wood, G. Schliert, and L. Kinsell, Metabolism,14, 1095 (1965).Google Scholar

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • V. E. Nikolaev

There are no affiliations available

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