Relations between hematopoiesis and osteogenesis in some species of rodents
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Different relations between hematopoiesis and osteogenesis were observed in bone marrow grafts from rats, guinea pigs, and striped hairy-footed hamsters, transplanted beneath the renal capsule of irradiated mice. Active osteogenesis took place in grafts from rats and guinea pigs whereas hematopoiesis was observed irregularly (rats) or it ceased to occur (guinea pigs). In grafts from the hamsters, on the other hand, intensive hematopoiesis was maintained but the osteogenic properties of the stroma were weak. In some species the presence of bone tissue is considered to be not strictly essential for the normal maintenance of myeloid hematopoiesis whereas in others the initial development of a bony stroma is an essential condition for subsequent functioning of the hematopoietic tissue.
Key wordsbone marrow extramedullary transplantation xenogeneic grafts osteogenesis hematopoiesis
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