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Type-specific antigen of gross leukemia virus in tumors and normal tissues and its identification by immunodiffusion methods

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

A monospecific serum was obtained against type-specific antigen of Gross leukemia virus (AGLV). Tumors of different etiology were investigated with the aid of a test system for AGLV. AGLV was found in a spontaneous kidney tumor (lymphosarcoma) of CC57BR mice and in tumors induced by chemical carcinogens. The results suggest activation of the MuLV virus genome in strains of mice with a low predisposition to leukemia.

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Authors
  1. O. M. Lezhneva
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Lezhneva, O.M. Type-specific antigen of gross leukemia virus in tumors and normal tissues and its identification by immunodiffusion methods. Bull Exp Biol Med 81, 239–242 (1976). https://doi.org/10.1007/BF00801083

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  • DOI: https://doi.org/10.1007/BF00801083

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