Abstract
Subcutaneous injection of fixed rabies virus into albino rats weighing 100–120 g is followed by a decrease in theγ-aminobytyric acid (GABA) concentration in the animals' brains. An increase in the activity of GABA-α-ketoglutarate transaminase also is observed in the brain tissue of animals vaccinated against rabies.
Similar content being viewed by others
Literature Cited
E. L. Avenirova, M. N. Maslova, V. I. Rozengard, et al., Vopr. Med. Khimii, No. 6, 633 (1966).
T. M. Khizhnyakova, M. Sh. Promyslov, and L. P. Gorshunova, Vopr. Med. Khimii, No. 6, 561 (1974).
M. Sh. Promyslov, T. V. Solov'eva, and R. I. Aniskina, Vopr. Med. Khimii, No. 6, 619 (1968).
T. S. Paskhina, Biokhimiya, No. 6, 702 (1954).
N. N. Yakovlev, Ukr. Biokhim. Zh., No. 2, 175 (1963).
C. F. Baxter and E. Roberts, J. Biol. Chem.,236, 3287 (1961).
E. Flory, Naturwissenschaften,40, 295 (1953).
S. Saito and Y. Tokunaga, J. Pharmacol. Exp. Ther.,157, 546 (1967).
E. Roberts, Inhibition in the Nervous System and γ-Aminobutyric Acid, US Air Force Office of Scientific Research, Proceedings of International Symposium, Oxford (1960), p. 144.
Rights and permissions
About this article
Cite this article
Khizhnyakova, T.M., Promyslov, M.S. & Gorshunova, L.P. Effect of immunization against rabies on γ-aminobutyric metabolism in the animal brain. Bull Exp Biol Med 81, 192–193 (1976). https://doi.org/10.1007/BF00801067
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00801067