Abstract
Multicellular formations responsible for the generation of spontaneous pacemaker activity were found in the cusps of the atrioventricular valves of the rabbit heart by means of a microelectrode technique and electron microscopy. Cells of different morphological structure were found: P cells, cells of the Purkinje type, and transitional cells. These formations were found to have a rich innervation, mainly cholinergic in nature. Definite correlation was found between the morphological structure and electrophysiological parameters of these cells.
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Beskrovnova, N.N., Korolev, V.V., Kosharskaya, I.L. et al. Morphofunctional characteristics of pacemaker formations in the atrioventricular valves of the heart. Bull Exp Biol Med 83, 712–716 (1977). https://doi.org/10.1007/BF00800759
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DOI: https://doi.org/10.1007/BF00800759