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Morphofunctional characteristics of pacemaker formations in the atrioventricular valves of the heart

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Multicellular formations responsible for the generation of spontaneous pacemaker activity were found in the cusps of the atrioventricular valves of the rabbit heart by means of a microelectrode technique and electron microscopy. Cells of different morphological structure were found: P cells, cells of the Purkinje type, and transitional cells. These formations were found to have a rich innervation, mainly cholinergic in nature. Definite correlation was found between the morphological structure and electrophysiological parameters of these cells.

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Beskrovnova, N.N., Korolev, V.V., Kosharskaya, I.L. et al. Morphofunctional characteristics of pacemaker formations in the atrioventricular valves of the heart. Bull Exp Biol Med 83, 712–716 (1977). https://doi.org/10.1007/BF00800759

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  • DOI: https://doi.org/10.1007/BF00800759

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