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Effect of adaptation to high-altitude hypoxia and subsequent disadaptation on conditioned reflex retention

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

After adaptation to high-altitude hypoxia the degree of retention of a conditioned active avoidance reflex is considerably increased. Only half as many combinations of the conditioned and unconditioned stimuli were required to reach the necessary level when the retention of the reflex was tested 24 h after its formation in adapted rats as in the control. This level of adaptation was produced 1 and 5 days after the end of a course of exposures to hypoxia. During disadaptation, the increase in the degree of retention of the reflex which had been achieved disappeared 10 and 27 days after the end of exposure to hypoxia.

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Meerson, F.Z., Solomatina, E.S. & Il'in, E.A. Effect of adaptation to high-altitude hypoxia and subsequent disadaptation on conditioned reflex retention. Bull Exp Biol Med 83, 620–622 (1977). https://doi.org/10.1007/BF00800729

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  • DOI: https://doi.org/10.1007/BF00800729

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