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Half-life of rabbit heart mitochondria in experimental allergic myocardial damage

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The half-life (T1/2) of the proteins and cytochorme c of rabbit myocardial mitochondria was determined by the use of glycin-1-C14 and aminolevulinic acid-H3, respectively, as precursors. T1/2 of cytochrome c calculated from the dynamics of the decrease in content of the label in the course of several weeks of investigation, was 11.8 days and T1/2 of the mitochondrial proteins 14.4 days. The degree of reutilization of glycine-C14 in structural metabolism was about 20%. No change was found in the rate of degradation of the mitochondria in rabbits with allergic myocardial damage.

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Authors
  1. M. D. Grozdova
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  2. L. K. Starostina
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  3. I. L. Sharlova
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Grozdova, M.D., Starostina, L.K. & Sharlova, I.L. Half-life of rabbit heart mitochondria in experimental allergic myocardial damage. Bull Exp Biol Med 79, 560–562 (1975). https://doi.org/10.1007/BF00800503

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  • DOI: https://doi.org/10.1007/BF00800503

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