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RNA synthesis in the rat brain during changes in CNS function

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

RNA synthesis in the phenolic fractions of nuclei and cytoplasm from higher structures of the rat brain under normal conditions, during training in defensive movements in a maze, and in an active control (irregular presentation of stimuli evoking defensive movements) was investigated by electrophoresis in polyacrylamide gel. Behavioral stimulation and irregular presentation of the same stimuli to the animals as during training, but not leading to the formation of defensive skills, activates synthesis of 18S, 28S, and higher forms of RNA in the phenolic extracts of the nuclei. An increase in the incorporation of labeled precursor in the 18S region was found for cytoplasmic RNA.

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Authors
  1. V. V. Dergachev
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  2. O. A. Tyutyaeva
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Dergachev, V.V., Tyutyaeva, O.A. RNA synthesis in the rat brain during changes in CNS function. Bull Exp Biol Med 79, 527–530 (1975). https://doi.org/10.1007/BF00800492

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  • DOI: https://doi.org/10.1007/BF00800492

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