Effect of acetylsalicylic acid on development of infarct-like myocardial necroses induced in rats by a single injection of isoproterenol

  • R. A. Martynyuk
  • L. A. Semenova
  • Yu. G. Tsellarius
Pathological Physiology and General Pathology


The development of infarct-like foci of necrosis and the primary development of lesions of the myocardial cells through the direct action of isoproterenol and manifested during the first hour are considerably reduced in animals receiving acetylsalicylic acid. This suggests that acetylsalicylic acid not only prevents platelet aggregation but also increases the resistance of the myocardial cells to the harmful action of catecholamines.

Key Words

Isoproterenol acetylsalicylic acid infarct-like necroses 


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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • R. A. Martynyuk
  • L. A. Semenova
  • Yu. G. Tsellarius

There are no affiliations available

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