Abstract
Histochemical characteristics of acid mucopolysaccharides (MPS) of the renal medulla were compared with the indices of kidney function in dogs during water and osmotic diuresis and polyuria induced by administration of heparin. Changes in staining for MPS were found to correspond to the intensity of reabsorption of osmotically free water. The results suggest that changes in the physicochemical properties of MPS are one of the significant factors determining the permeability of structures of the renal medulla to movement of water from the lumen of the tubules into the interstices.
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Ivanova, L.N., Melidi, N.N. Role of acid mucopolysaccharides of the kidney in the mechanism of reabsorption of osmotically free water. Bull Exp Biol Med 79, 491–494 (1975). https://doi.org/10.1007/BF00800481
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DOI: https://doi.org/10.1007/BF00800481