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Experimental analysis of the humoral mechanism of microcirculatory disturbances after thermal and mechanical injury inducing shock in parabiotic rats

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Mechanical or thermal injury to one of a pair of parabiotic rats with a crossed circulation but separate innervation was followed by the development of a state resembling shock in the other partner. Microcirculatory changes characteristic of either traumatic or burn shock developed in its mesentery under these circumstances. The results are interpreted as evidence in support of a humoral rather than a nervous mechanism of the microcirculatory disturbances in these types of shock.

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Shtykhno, Y.M., Titova, I.P. Experimental analysis of the humoral mechanism of microcirculatory disturbances after thermal and mechanical injury inducing shock in parabiotic rats. Bull Exp Biol Med 86, 1302–1304 (1978). https://doi.org/10.1007/BF00800441

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  • DOI: https://doi.org/10.1007/BF00800441

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