Abstract
Acute ischemia was produced by application of a tourniquet to the limb or a clamp to the pedicle of the kidney for a time corresponding to the critical level of metabolism in the test tissue. Restoration of the blood flow in the ischemized kidney led to accumulation of an excess of high-molecular-weight glucose polymer of glycogen type. The character of branching in its molecule, determined from the spectrum of its complexes with iodine, points to changes in processes of glycogen biosynthesis. For the needs of glycogenesis, lactate of the ischemized kidney can be used. It is shown that this abnormal glycogen is actively utilized by kidney tissue. Accumulation of glycogen in muscle tissue after acute ischemia does not exceed the normal level and its structure is unchanged.
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Selivanova, L.P., Saburova, L.M. Glycogen metabolism in ischemized organs. Bull Exp Biol Med 86, 1299–1301 (1978). https://doi.org/10.1007/BF00800440
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DOI: https://doi.org/10.1007/BF00800440