Abstract
After fractional irradiation of the bone marrow of mice (300 radin vitro + 300 radin vivo) damage to the hematopoietic stem cells is substantially less if the interval between irradiations is 5 h than if the interval is 30 min, as a result of recovery from sublethal radiation injury (the Elkind repair effect). In thymectomized adult mice ability of hematopoietic stem cells to undergo Elkind repair is severely disturbed 2.5–5 months after the operation. Transplantation of the thymus abolishes the effect of thymectomy.
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Todriya, T.V. Effect of the thymus on the ability of hematopoietic stem cells to recover after sublethal radiation injury. Bull Exp Biol Med 86, 1500–1502 (1978). https://doi.org/10.1007/BF00800297
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DOI: https://doi.org/10.1007/BF00800297