Summary
A study was made of the effect produced by ionizing radiation (190 and 400 r) on the 24-hour periodicity of mitotic activity of the mouse corneal epithelium. As noted, the 24-hour mitotic rhythm was retained on the 5th postirradiation day (doses of 190 and 400 r being used). The time of the maximal (8 A.M.) and the minimal (8 P.M.) number of mitosis in the corneal epithelium of experimental mice coincided with control indices. The difference between the maximal and minimal mitotic activity in the two experiments was highly significant. The range of the 24-hour variations of the number of mitoses showed no significant change in the experimental animals. After irradiation of mice in a dose of 400 r there was a tendency to a rise of the mean 24-hour intensity of cellular multiplication.
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Kosichenko, L.P. Diurnal periodicity of mitosis in mice after irradiation with γ-rays. Bull Exp Biol Med 55, 106–108 (1964). https://doi.org/10.1007/BF00800215
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DOI: https://doi.org/10.1007/BF00800215