Summary
During gradual reproduction of experimental aortic stenosis in dogs there occurs a considerable reduction of the general vascular resistance. This shift is clearly observed not only in stenosis of the aorta, it is an important compensatory factor maintaining the normal cardiac output in economic use of the myocardial reserves. A drop in vascular resistance during intensive cardiac hyperfunction may be due to the reflux from the receptors of the left ventricle to the arteriolar musculature.
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Meerson, F.Z., Mikoélyan, A.L., Markovskaya, G.I. et al. The myocardium and the hemodynamics during cardiac hyperfunction and insufficiency. Report 2. Lowering of the resistance of the vascular field as an economic compensatory factor in diseases of the circulatory system. Bull Exp Biol Med 55, 26–29 (1964). https://doi.org/10.1007/BF00800194
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DOI: https://doi.org/10.1007/BF00800194