Abstract
Sialomucin, dermatan sulfate, keratan sulfate, and neutral mucopolysaccharides (MPS) were determined by histochemical methods in the goblet cells of the rabbit appendix. Sialomucin and neutral MPS were found in the glands. After immunization with human γ-globulin, increased secretory activity of the mucous membrane of the appendix was found in the productive phase of immunogenesis. Increased formation of mucus in the appendix was observed also after laparotomy and in the initial period of experimental appendicitis. However, against the background of increased functional activity of the secretory cells in the immunized animals, operative trauma gave the opposite effect, and in the course of experimental appendicitis no period of activation of mucus formation was found. The effect of these factors on secretory activity of the mucous membrane is accompanied by qualitative changes in the mucus secreted.
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Platash, V.I. Effect of operative trauma, circulatory hypoxia, and immunization on the histochemical characteristics of secretory cells of the appendix. Bull Exp Biol Med 81, 115–117 (1976). https://doi.org/10.1007/BF00800186
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DOI: https://doi.org/10.1007/BF00800186