Abstract
A karyometric study was made of the juxtaglomerular apparatus of 17 allografted human kidneys at different times after transplantation. Kidneys of persons dying from head injuries or acute heart failure were used as the control. In the early periods (up to 2 months) there was a significant increase in volume of the nuclei of the epithelioid-modified cells of the afferent arteriole and of Goormaghtigh's cells. A tendency also was observed for the volume of the cell nuclei of the macula densa to increase. At the late stages the juxtaglomerular apparatus still remained in allografted kidneys with a slightly damaged parenchyma. If sclerosis and atrophy of the parenchyma of the graft was marked, the juxtaglomerular apparatus was reduced.
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Literature Cited
A. M. Vikhert, Arkh. Pat., No. 9, 19 (1963).
A. M. Vikhert and Yu. A. Serebrovskaya, Arkh. Pat., No. 2, 17 (1963).
Ya. E. Khesin, Dimensions of the Nuclei and the Functional State of Cells [in Russian], Moscow (1967).
D. Crocker et al., New Engl. J. Med.,267, 794 (1962).
D. Crocker, Arch. Path.,93, 103 (1972).
N. Goormaghtigh, Am. J. Path.,16, 409 (1940).
P. Hartroft and W. Hartroft, J. Exp. Med.,97, 415 (1953).
H. D. Itskovitz et al., Ann. Intern. Med.,59, 8 (1963).
J. Pitcock and P. Hartroft, Am. J. Path.,34, 863 (1958).
L. Tobian, J. Thompson, et al., J. Clin. Invest.,37, 660 (1958).
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Orduyan, S.L., Blyumkin, V.N. Morphometry of the juxtaglomerular apparatus of the allografted human kidney. Bull Exp Biol Med 81, 108–110 (1976). https://doi.org/10.1007/BF00800184
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DOI: https://doi.org/10.1007/BF00800184