Abstract
The radiosensitivity of splenic colony-forming units (CFUs) settling in the bone marrow and spleen does not differ significantly. The value of D0 for CFUs forming colonies in the spleen varies between 105 and 120 R. D0 for CFUs forming colonies in bone marrow is 120–135 R. It is postulated that two fractions for CFUs are represented in bone marrow, one radiosensitive, the other radioresistant. In the spleen mainly the radiosensitive fraction of CFUs is found.
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Literature Cited
R. V. Petrov and V. N. Shvets, Probl. Gematol., No. 10, 48 (1973).
V. N. Shvets, Byull. Éksperim. Biol. Med., No. 5, 40 (1975).
E. Guzman and L. G. Lajtha, Cell Tissue Kinet.,3, 91 (1970).
B. I. Lord and R. Schofield, Nature,221, 1060 (1969).
J. E. Till and E. A. McCulloch, Radiat. Res.,14, 213 (1961).
J. J. Trentin, Am. J. Path.,65, 621 (1971).
N. S. Wolf and J. J. Trentin, J. Exp. Med.,127, 205 (1968).
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Shvets, V.N. Radiosensitivity and direction of differentiation of colony-forming cells in the spleen. Bull Exp Biol Med 81, 92–94 (1976). https://doi.org/10.1007/BF00800179
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DOI: https://doi.org/10.1007/BF00800179