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Action of hydrocortisone on DNA synthesis by sebaceous gland epithelial cells

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

It was shown by autoradiography that after a single injection of hydrocortisone (10 mg/100 g body weight) transition from the G1 to the S period is delayed and the duration of the S period is increased for epithelial cells in the acinar part of the sebaceous gland (sebocytes) and the stratified squamous epithelium of the efferent ducts. Later, after the proliferative processes have subsided, their intensity increases again and proliferative activity exceeds the initial level. Hydrocortisone has a more powerful action on the proliferative activity of the stratified squamous epithelial cells of the efferent ducts of the sebaceous gland than on proliferative activity of the acinar sebocytes.

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Kinzhibulatova, R.Z. Action of hydrocortisone on DNA synthesis by sebaceous gland epithelial cells. Bull Exp Biol Med 81, 90–91 (1976). https://doi.org/10.1007/BF00800178

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  • DOI: https://doi.org/10.1007/BF00800178

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