Abstract
Responses of venules, capillaries, arterioles, and mast cells of the rat mesentery to irradiation by the LGI-21 pulsed ultraviolet laser (λ=337 nm) was studied by intravital microscopy. The diameter of the laser beam varied from 2 to 100 μ. The processes studied were recorded and analyzed by a photographic and videorecording method. Depending on the intensity and duration, irradiation caused either an increase in permeability of the vessel walls, or thrombus formation, or hemorrhage. Besides injury to the vessel wall, an important role in thrombus formation was played by factors appearing on destruction of erythrocytes and other blood cells. The change in diameter and permeability of the vessels during laser irradiation of the mast cells could be associated with liberation of the histamine and serotonin contained in them.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
M. P. Gorizontova, O. V. Alekseev, and A. M. Chernukh, Byull. Éksperim. Biol. Med., No. 3, 22 (1975).
N. V. Tsyganova, Byull. Éksperim. Biol. Med., No. 12, 29 (1973).
A. M. Chernukh, P. N. Aleksandrov, and O. V. Alekseev, The Microcirculation [in Russian], Moscow (1975).
A. M. Chernukh, V. S. Shinkarenko, and L. S. Ivanov, Pat. Fiziol., No. 2, 78 (1975).
M. M. Guest, T. P. Bond, and M. A. Crawford, Bibl. Anat. (Basel), No. 12, 131 (1973).
F. N. McKenzie, K. E. Arfors, T. Hovig, et al., Bibl. Anat. (Basel) No. 12, 186 (1973).
P. D. Stein and H. N. Sabbah, Circulat. Res.,35, 608 (1974).
M. P. Wiedeman, Microvasc. Res.,8, 132 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chernukh, A.M., Shinkarenko, V.S., Ivanov, L.S. et al. Simulation of microcirculatory disorders by the use of an ultraviolet laser. Bull Exp Biol Med 81, 19–22 (1976). https://doi.org/10.1007/BF00800154
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00800154