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Bulletin of Experimental Biology and Medicine

, Volume 85, Issue 2, pp 226–229 | Cite as

Comparative study of some structural and functional indices of the liver and adrenal cortex in physiologically normal mice of different genetic lines

  • V. A. Shkurupii
  • Z. Ya. Gizatulin
  • I. N. Indikova
  • T. A. Obut
  • A. S. Sorokin
  • G. S. Yakobson
Experimental Biology

Abstract

Interlinear differences with respect to morphometric characteristics of the subcellular organization of the hepatocytes and also to indices of adrenocortical function and rate of metabolism of steroid hormones in the liver were found in adult male CBA and C57BL mice. Steroid hormone production by the adrenals and the rate of their metabolism in the liver were found to be inversely proportional in the animals of the two lines. The pattern of structural and functional sponses of the liver of animals of these two strains to pathogenic factors.

Key Words

interlinear differences liver adrenals steroid hormones 

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Literature Cited

  1. 1.
    L. D. Liozner, L. G. Babaeva, V. F. Sidorova, et al., Byull. Éksp. Biol. Med., No. 2, 95 (1972).Google Scholar
  2. 2.
    T. A. Obut, Lab. Delo, No. 6, 351 (1974).Google Scholar
  3. 3.
    Yu. A. Pankov and I. Ya. Usvatova, Publications of the First Moscow Medical Institute on New Apparatus and Methods [in Russian], No. 3, Moscow (1975), p. 137.Google Scholar
  4. 4.
    V. F. Sidorova and N. V. Yudina, Byull. Éksp. Biol. Med., No. 4, 475 (1976).Google Scholar
  5. 5.
    O. V. Smirnov, A. N. Smirnov, and V. B. Rozen, Byull. Éksp. Biol. Med., No. 5, 548 (1977).Google Scholar
  6. 6.
    V. A. Shkurupii, N. B. Khristolyubova, and G. S. Yakobson, Izv. Sib. Otd. Akad. Nauk SSSR. Ser. Biol., No. 3, 109 (1973).Google Scholar
  7. 7.
    G. S. Yakobson, V. A. Shkurupii, and N. B. Khristolyubova, Byull. Éksp. Biol. Med., No. 3, 114 (1974).Google Scholar
  8. 8.
    L. E. Edwards and A. J. Dalton, J. Nat. Cancer. Inst.,3, 19 (1942).Google Scholar
  9. 9.
    A. Flaks, Eur. J. Cancer,4, 579 (1968).Google Scholar
  10. 10.
    O. H. Lowry, N. J. Rosebrough, A. L. Farr, et al., J. Biol. Chem.,143, 68 (1951).Google Scholar
  11. 11.
    R. O. Recknagel and A. K. Ghostal, Exp. Mol. Pathol.,5, 413 (1966).Google Scholar
  12. 12.
    T. S. Tamulski, C. E. Morreal, and T. L. Dao, Cancer Res.,33, 3117 (1973).Google Scholar
  13. 13.
    P. J. Thung, Acta Physiol. Pharmacol. Neerl.,10, 248 (1962).Google Scholar
  14. 14.
    E. R. Weibel, W. Staubli, H. R. Gnaugi, et al., J. Cell Biol.,42, 68 (1969).Google Scholar

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • V. A. Shkurupii
  • Z. Ya. Gizatulin
  • I. N. Indikova
  • T. A. Obut
  • A. S. Sorokin
  • G. S. Yakobson

There are no affiliations available

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