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Free fatty acid content in muscles after administration of ACTH and hydrocortisone

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The content of free fatty acids (FFA) in the gastrocnemius muscles 30 min after intraperitoneal injection of 1 unit ACTH/100 g and 1 mg hydrocortisone acetate/100 g body weight was investigated by gas chromatography in experiments on rats. In resting muscles ACTH was shown to increase the stearic acid content whereas hydrocortisone increased the content of both stearic and oleic acids. Changes in the concentration of other FFA were not significant. During a short period of activity involving single regular contractions the stearic acid concentration in the gastrocnemius muscles of intact rats increased. In the experiments with ACTH and hydrocortisone this increase was considerably smaller and was not significant. ACTH and hydrocortisone stimulate the utilization of stearic acid by the muscles during activity.

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Literature Cited

  1. E. E. Antonova, Byull. Éksp. Biol. Med., No. 11, 63 (1970).

    Google Scholar 

  2. A. A. Viru and T. A. Smirnova, Tr. Sarat. Med. Inst.,87, (104), 74 (1974).

    Google Scholar 

  3. G. G. Vol'skii and L. M. Osadchaya, in: Mitochondria [in Russian], Moscow (1976), p. 164.

  4. G. G. Gatsko and L. D. Chaika, Probl. Éndokrinol., No. 5, 61 (1976).

    Google Scholar 

  5. N. K. Davtyan, Probl. Éndokrinol., No. 4, 84 (1964).

    Google Scholar 

  6. S. M. Leites, Klin. Med., No. 10, 25 (1958).

    Google Scholar 

  7. S. M. Leites,and Chou-Su, Vopr. Med. Khim., No. 3, 289 (1962).

    Google Scholar 

  8. L. G. Leshkevich, Ukr. Biokhim. Zh., No. 6, 714 (1970).

    Google Scholar 

  9. V. F. Prokopenko and N. M. Pokrasen, Lab. Delo, No. 2, 90 (1975).

    Google Scholar 

  10. J. D. Corbin and E. I. Krebs, Biochem. Biophys. Res. Commun.,36, 328 (1969).

    Google Scholar 

  11. P. Desbals, P. Mialne, and B. Desbals, J. Physiol. (Paris),63, 21 (1971).

    Google Scholar 

  12. J. Hamuro, Endocrinology,90, 200 (1972).

    Google Scholar 

  13. J. C. Khoo and D. Steinberg, Methods Enzymol.,35, 181 (1975).

    Google Scholar 

  14. B. S. Powers and N. R. Di Luzio, Fed. Proc.,16, 243 (1957).

    Google Scholar 

  15. J. Ramachandran and V. Lee, Biochim. Biophys. Acta,428, 339 (1976).

    Google Scholar 

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Authors
  1. V. I. Korkach
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  2. A. A. Yurchenko
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Korkach, V.I., Yurchenko, A.A. Free fatty acid content in muscles after administration of ACTH and hydrocortisone. Bull Exp Biol Med 85, 154–156 (1978). https://doi.org/10.1007/BF00800111

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  • DOI: https://doi.org/10.1007/BF00800111

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