Bulletin of Experimental Biology and Medicine

, Volume 85, Issue 2, pp 154–156 | Cite as

Free fatty acid content in muscles after administration of ACTH and hydrocortisone

  • V. I. Korkach
  • A. A. Yurchenko
Biochemistry and Biophysics


The content of free fatty acids (FFA) in the gastrocnemius muscles 30 min after intraperitoneal injection of 1 unit ACTH/100 g and 1 mg hydrocortisone acetate/100 g body weight was investigated by gas chromatography in experiments on rats. In resting muscles ACTH was shown to increase the stearic acid content whereas hydrocortisone increased the content of both stearic and oleic acids. Changes in the concentration of other FFA were not significant. During a short period of activity involving single regular contractions the stearic acid concentration in the gastrocnemius muscles of intact rats increased. In the experiments with ACTH and hydrocortisone this increase was considerably smaller and was not significant. ACTH and hydrocortisone stimulate the utilization of stearic acid by the muscles during activity.

Key Words

ACTH hydrocortisone free fatty acids muscular contraction 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • V. I. Korkach
  • A. A. Yurchenko

There are no affiliations available

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