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Collagen-polysaccharide gel as a model of the ground substance of connective tissue

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

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Abstract

Samples of gel formed at 37°C in solutions containing tropocollagen and various polysaccharides were studied with the electron microscope. Contracting gel clots were formed in solutions containing chondroitin sulfate, proteoglycan from tracheal cartilage, and gum arabic as the polysaccharide component. Examination under the electron microscope showed that these clots were permeated by transversely striated collagen fibrils with a period of 64 nm. The connection between the density of the gel thus formed and the nature of the polysaccharide component is discussed. Gel forming in solutions containing tropocollagen and various polysaccharides can be regarded as a suitable model of the ground substance of connective tissue.

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Authors
  1. V. A. Lazarev
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Lazarev, V.A. Collagen-polysaccharide gel as a model of the ground substance of connective tissue. Bull Exp Biol Med 82, 1518–1520 (1976). https://doi.org/10.1007/BF00799797

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  • DOI: https://doi.org/10.1007/BF00799797

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