Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 4, pp 1481–1484 | Cite as

Effect of thyrotoxicosis on skeletal muscle proprioceptor activity

  • R. S. Arutyunyan
  • G. A. Gaidina
  • T. G. Katasonova
Pathological Physiology and General Pathology


The effect of prolonged administration of thyroid hormones on the discharges from muscle spindles of the cat soleus was investigated. In animals with thyrotoxicosis the response of the primary spindle endings to a constantly acting and to a sudden rapid stretching increased considerably in both the dynamic and the static phase. The discharge frequency of the secondary endings remained substantially unchanged. It is postulated that the observed changes in activity of the primary endings are connected with disturbances of metabolism in the muscle and also with its atrophy.

Key Words

thyroid hormones muscle receptors motor disturbances 


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • R. S. Arutyunyan
  • G. A. Gaidina
  • T. G. Katasonova

There are no affiliations available

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