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Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 4, pp 1481–1484 | Cite as

Effect of thyrotoxicosis on skeletal muscle proprioceptor activity

  • R. S. Arutyunyan
  • G. A. Gaidina
  • T. G. Katasonova
Pathological Physiology and General Pathology
  • 13 Downloads

Abstract

The effect of prolonged administration of thyroid hormones on the discharges from muscle spindles of the cat soleus was investigated. In animals with thyrotoxicosis the response of the primary spindle endings to a constantly acting and to a sudden rapid stretching increased considerably in both the dynamic and the static phase. The discharge frequency of the secondary endings remained substantially unchanged. It is postulated that the observed changes in activity of the primary endings are connected with disturbances of metabolism in the muscle and also with its atrophy.

Key Words

thyroid hormones muscle receptors motor disturbances 

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Literature Cited

  1. 1.
    R. S. Arutyunyan, Fiziol. Zh. SSSR, No. 5, 793 (1973).Google Scholar
  2. 2.
    R. S. Arutyunyan, Fiziol. Zh. SSSR, No. 7, 1032 (1975).Google Scholar
  3. 3.
    L. M. Gol'ber, G. A. Gaidina, and V. Ya. Ignatkov, Dokl. Akad. Nauk SSSR,196, 987 (1971).Google Scholar
  4. 4.
    V. I. Kandror, “Mechanisms of cardiovascular disorders in thyrotoxicosis,” Doctoral Dissertation, Moscow (1967).Google Scholar
  5. 5.
    R. R. Rachev, Mitochondria and Thyroid Hormones [in Russian], Leningrad (1969).Google Scholar
  6. 6.
    D. I. Fridberg, Neurological Analysis of Thyrotoxicosis [in Russian], Moscow (1961).Google Scholar
  7. 7.
    N. A. Shereshevskii, The Thyrotoxicoses [in Russian], Moscow (1951).Google Scholar
  8. 8.
    P. Bessou and Y. Laporte, in: Symposium of Muscle Receptors (Proceedings) (ed. By D. Barken), Hong Kong (1962), p. 105.Google Scholar
  9. 9.
    S. Cooper, Quart. J. Exp. Physiol.,46, 389 (1961).Google Scholar
  10. 10.
    S. Cooper and M. H. Gladden, Quart. J. Exp. Physiol.,59, 367 (1974).Google Scholar
  11. 11.
    R. Granit and J. P. van der Meulen, Acta Physiol. Scand.,55, 231 (1962).Google Scholar
  12. 12.
    R. J. Harvey and P. Matthews, J. Physiol. (London),157, 370 (1961).Google Scholar
  13. 13.
    C. C. Hunt, J. Gen. Physiol.,38, 117 (1954).Google Scholar
  14. 14.
    B. Katz, J. Physiol. (London),111, 261 (1950).Google Scholar
  15. 15.
    J. Laplaud, O. Rougier, and V. M. Gargouil, C. R. Acad. Sci. (Paris),252, 334 (1961).Google Scholar
  16. 16.
    O. C. Lippold, J. G. Nicholls, and J. W. Redfearn, J. Physiol. (London),153, 200 (1960).Google Scholar
  17. 17.
    P. B. C. Matthews, in: Mammalian Muscle Receptors and Their Central Actions (ed. by P. B. C. Matthews), Williams and Wilkins, Baltimore (1972), p. 140.Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • R. S. Arutyunyan
  • G. A. Gaidina
  • T. G. Katasonova

There are no affiliations available

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