Summary
Incomplete antibodies to sheep erythrocytes were revealed in the serum of the following adults: in 42.5% out of the 155 patients in the Institute of Rheumatism, in 16.2% out of the 148 patients in the psychiatric clinic, and in 7.2% out of the 83 apparently healthy persons. These antibodies were specific to sheep erythrocytes in comparison with the guinea pig, rat, and human erythrocytes: this was confirmed in absorption experiments. Among patients with infectious nonspecific polyarthritis incomplete antibodies were revealed mostly in individuals with the rheumatoid factor in the blood (in 21 out of 28) as compared to those without the rheumatoid factor (in 9 out of 31). It is assumed that incomplete antibodies to Forssman antigen are not normal antibodies, but appear in pathological conditions.
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Kuznetsova, N.I. Incomplete antibodies against sheep's red cells in human serum. Bull Exp Biol Med 55, 307–310 (1964). https://doi.org/10.1007/BF00799669
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DOI: https://doi.org/10.1007/BF00799669