Abstract
Assimilation of the nitrogen preparations moriamine S-2 and improved casein hydrolysate when given parenterally to 100 albino rats was studied. Both healthy animals and animals with toxic hepatitis induced by CCl4 were used. Administration of the nitrogen preparations to healthy animals converted the negative nitrogen balance to positive and restored the normal content of amino nitrogen in the blood and tissues when disturbuted as a result of protein deprivation. In toxic hepatitis the rate of assimilation of the preparations was considerably reduced. Parenteral feeding for eight days did not convert the negative nitrogen balance into positive and did not abolish the hypoproteinemia, although it restored the normal amino-nitrogen concentration in the blood and tissues.
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Glants, R.M., Skovronskaya, E.V., Vovk, G.P. et al. Anabolic effectiveness of nitrogen preparations for parenteral feeding in toxic hepatitis. Bull Exp Biol Med 86, 1030–1032 (1978). https://doi.org/10.1007/BF00799581
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DOI: https://doi.org/10.1007/BF00799581