Abstract
Disorganization of the motochondria, myofibrils, and sarcolemma, intra-and intercellular edema, swelling and pycnotic changes in the endothelium, occlusion of the capillaries by blood cells, and thickening and condensation of the basement membranes were observed in the myocardium of rats with nephrotoxic glomerulonephritis induced by Masugi's method. The changes reached a maximum on the 10th–20th day after the beginning of production of glomerulonephritis. After the 20th day intracellular regenerative processes became intensified. Correlation was found between the subcellular, histological, and clinical manifestations of glomerulonephritis.
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Literature Cited
M. S. Vovsi and G. P. Shchul'tsev, in: Experience of Soviet Medicine in the Second World War 1941–1945 [in Russian], Vol. 22, Moscow (1952), p. 60.
V. Shch. Gal'dis, A. A. Faerman, and M. N. Sychev, in: Proceedings of the First All-Union Congress Nephrologists [in Russian], Minsk (1974), p. 53.
V. F. Zelenin and I. B. Kabakov, Klin. Med., No. 1, 55 (1939).
Z. T. Samoilova, G. P. Shchul'tsev, L. V. Khalyutina, et al., in: Simulation, Methods of Study, and Experimental Therapy of Pathological Processes [in Russian], Moscow (1973), p. 53.
V. N. Sychev, Vrach. Delo, No. 2, 97 (1973).
J. Gore and O. Saphir, Am. Heart J.,36, 390 (1948).
J. Daskalov, Scr. Sci. Med. (Sofia),7, 141 (1968).
V. De Fazio, R. Christensen, et al., Circulation,20, 190 (1959).
J. La Due and R. Aschman, Am. Heart J.,31, 6685 (1946).
T. Murphy and F. Murphy, Ann. Intern. Med.,41, 510 (1954).
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Lebkova, N.P., Samoilova, Z.T. Subcellular changes in the myocardium of rats with nephrotoxic glomerulonephritis. Bull Exp Biol Med 82, 1408–1411 (1976). https://doi.org/10.1007/BF00799493
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DOI: https://doi.org/10.1007/BF00799493