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Effect of a suboptimal temperature on the mitotic regime

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Keeping Chinese hamster cells for 2 h at a suboptimal temperature (21°C) leads to a fall in the mitotic index and delay of division at the metaphase state. Cooling cause a sharp increase in the number of pathological mitoses, mainly as a result of injury to the mitotic apparatus: C mitoses and dispersion of the chromosomes in metaphase. After transfer of the cells to optimal temperature conditions the mitotic regime is completely restored after 1 h, but at this time the number of pathological mitoses is still appreciably greater than in the control.

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Authors
  1. M. N. Boltovskaya
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Boltovskaya, M.N. Effect of a suboptimal temperature on the mitotic regime. Bull Exp Biol Med 83, 233–235 (1977). https://doi.org/10.1007/BF00799432

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  • DOI: https://doi.org/10.1007/BF00799432

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