Abstract
The effect of contamination of germfree guinea pigs by single strains of the intestinal microflora (Bacillus mesentericus, Bacillus subtilis, Staphylococcus albus, andStreptococcus faecalis), on the formation of the opsonic activity of the blood serum was studied. An increase in opsonic activity against all microorganisms was observed on the 11th day after the corresponding monocontamination, and the serum had a stimulating effect on the intracellular digestion of cells ofB. mesentericus andB. subtilis. With respect to pathogenic microorganisms (E. coli 055) onlyS. faecalis cells were able to stimulate the opsonic activity of the serum. The results point to the existence of a connection between the composition of the microflora and the opsonic activity of the animals' blood serum. The level of this index also depends on the properties of the object of phagocytosis.
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Andreev, V.N., Podoprigora, G.I. Opsonic activity of the serum of germfree guinea pigs contaminated by single strains of the intestinal microflora. Bull Exp Biol Med 83, 206–208 (1977). https://doi.org/10.1007/BF00799424
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DOI: https://doi.org/10.1007/BF00799424