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Changes in some gas exchange indices in dogs in the initial stage of traumatic shock by Cannon's method

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Experiments in which traumatic shock was produced by Cannon's method in 35 dogs showed that metabolic acidosis during shock develops against the background of a sharply increased oxygen consumption in the initial stage of trauma when the arterial pressure is much higher than originally. The brain is under the most favorable conditions of gas exchange in traumatic shock, whereas the skeletal muscle of the limbs is less favorably situated. It is concluded that in severe trauma, despite sustained function of the respiratory and cardiovascular systems, the tissues of the brain and skeletal muscle do not receive sufficient oxygen as a result of circulatory disturbances and a sharp rise in their oxygen demand.

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Yaremenko, B.R., Keerig, Y.Y. Changes in some gas exchange indices in dogs in the initial stage of traumatic shock by Cannon's method. Bull Exp Biol Med 83, 134–136 (1977). https://doi.org/10.1007/BF00799401

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  • DOI: https://doi.org/10.1007/BF00799401

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