Bulletin of Experimental Biology and Medicine

, Volume 83, Issue 3, pp 419–422 | Cite as

Electron-microscopic autoradiographic investigation of intracellular RNA synthesis in the mouse cerebral cortex

  • A. A. Pal'tsyn
  • E. Ya. Sanovich
  • V. P. Tumanov
Morphology and Pathomorphology

Abstract

Electron-autoradiographic investigation of DNA synthesis in mouse cerebral cortical neurons showed the highest concentration of label in the nucleolus. Many grains of silver were concentrated above the nucleoplasm. The content of radioactive substances in the cytoplasm of the neurons 2.5 h after injection of uridine-5-3H into the animals was lower than in other types of cells after the same length of contact with the labeled precursor. A considerable difference was observed in the number of grains of silver above serial sections of a single nucleolus and in the character of distribution of the label in neurons situated side by side.

Key Words

neurons RNA metabolism electron-microscopic autoradiography 

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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • A. A. Pal'tsyn
  • E. Ya. Sanovich
  • V. P. Tumanov

There are no affiliations available

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