Abstract
A syndrome of low cardiac output developed between the first and third hours after resuscitation in 16 dogs subjected to circulatory arrest for 15 min. In half of the cases its development was preceded by an increase in the cardiac output in the initial period of resuscitation. Without hyperperfusion at the beginning of resuscitation, the animals died 9–23 h after the beginning of the experiment. Among the surviving animals, edema of the cerebral cortex always developed in dogs with a reduced cardiac output 24 h after resuscitation, but no cerebral edema was observed in dogs with a high cardiac output.
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Novoderzhkina, I.S., Trubina, I.E., Bolyakina, G.K. et al. Relationship of changes in the central hemodynamics to the development of posthypoxic cerebral edema in the postresuscitation period. Bull Exp Biol Med 83, 296–298 (1977). https://doi.org/10.1007/BF00799341
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DOI: https://doi.org/10.1007/BF00799341