Abstract
The action of x-ray irradiation on DNA synthesis and mitotic activity of the uterine epithelium was studied by autoradiography with thymidine-H3 at different stages of the sex cycle. In response to local irradiation in a dose of 400 R the decrease in the index of labeled nuclei and in the mitotic index differed depending on the stage of the sex cycle at which irradiation was given.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
V. M. Budik, Byull. Éksperim. Biol. i Med., No. 12, 85 (1969).
O. A. Epifanova, Hormones and Cell Multiplication [in Russian], Moscow (1965).
O. A. Epifanova, Byull. Éksperim. Biol. i Med., No. 11, 113 (1958).
S. S. Laguchev, Principles Governing the Hormonal Regulation of Mitotic Activity of the Epithelium of the Uterus, Vagina, and Mammary Glands of Mice, Author's Abstract of Doctoral Dissertation [in Russian], Moscow (1966).
J. L. Labinski and H. W. Gruchow, Cell Tissue Kinet.,3, 175 (1970).
L. G. Lajtha, R. Oliver, F. Ellis, et al., Radiat. Res.,8, 11 (1958).
C. A. Perrotta, Radiat. Res.,28, 232 (1966).
Takao Mori, Akira Matsimoto, et al., Proc. Jap. Acad.,47, 401 (1971).
Rights and permissions
About this article
Cite this article
Mkrtchyan, S.A. Action of x-ray irradiation on DNA synthesis and mitotic activity in uterine epithelial cells at different stages of the sex cycle. Bull Exp Biol Med 78, 813–815 (1974). https://doi.org/10.1007/BF00799329
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00799329