Effect of bacterial polysaccharide on the number of antibody-producing cells in the spleen of irradiated and unirradiated mice

  • M. A. Tumanyan
  • A. V. Izvekova
Microbiology and Immunology


The effect of bacterial polysaccharide on the number of spleen cells producing antibodies against sheep's red cells was investigated in irradiated and unirradiated mice. The polysaccharide increased the number of antibody-producing cells both in lethally irradiated (γ rays) and in unirradiated mice, unimmunized or immunized with sheep's red cells. This increase was connected with the stimulation of proliferative processes in the recipient by the polysaccharide.

Key Words

antibody-forming cells bacterial polysaccharide irradiation 


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Literature Cited

  1. 1.
    V. M. Berman and E. M. Slavskaya, in: Current Problems in Immunology and Pathology [in Russian], Leningrad (1970), p. 92.Google Scholar
  2. 2.
    M. S. Gordeeva, A. V. Izvekova, and M. A. Tumanyan, in: Problems in Radiation Immunology and Microbiology, Proceedings of the 8th Conference [in Russian], Moscow (1972), p. 27.Google Scholar
  3. 3.
    A. P. Duplishcheva, K. K. Ivanov, and N. G. Sinilova, Radiobiologiya, No. 2, 243 (1965).Google Scholar
  4. 4.
    N. N. Klemparskaya and G. A. Shal'nova, Radiobiologiya, No. 2, 332 (1962).Google Scholar
  5. 5.
    L. A. Pevnitskii, V. V. Solov'ev, and L. N. Fontalin, Byull. Éksperim. Biol. i Med., No. 8, 85 (1965).Google Scholar
  6. 6.
    E. F. Romantsev, Radiation and Chemical Protection [in Russian], Moscow (1963).Google Scholar
  7. 7.
    M. A. Tumanyan, A. P. Duplishcheva, O. V. Chakhava, et al., Vestn. Akad. Med. Nauk SSSR, No. 7, 25 (1970).Google Scholar
  8. 8.
    M. A. Tumanyan, A. V. Izvekova, A. P. Duplishcheva, et al., in: 4th International Congress of Radiation Research, Abstracts, Evian (1970), p. 871.Google Scholar
  9. 9.
    N. K. Jerne and A. A. Nordin, Science,140, 405 (1963).Google Scholar
  10. 10.
    J. G. Michael, J. J. L. Whitby, and M. Landy, Nature,191, 96 (1961).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1974

Authors and Affiliations

  • M. A. Tumanyan
  • A. V. Izvekova

There are no affiliations available

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