Effect of space flight on composition of soluble proteins of the spinal cord and spinal ganglia of rats
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The content of individual protein fractions extracted from the spinal cord, at the level of the lumbar enlargement, and the spinal ganglia of rats consecutively with distilled water, 0.85% NaCl solution, and 0.1 N NaOH solution was investigated. A significant decrease in the content of water-soluble proteins was found in the white and gray matter of the spinal cord 12 h after space flight. The content of salt-soluble and alkali-soluble proteins in the structures of the spinal cord and spinal ganglia per milligram wet weight of tissue was not significantly altered. A significant increase in the content of water-soluble proteins compared with the control was found in the gray matter of the spinal cord 25 days after space flight. The content of water-soluble proteins in the white matter of the spinal cord was increased to the control level. A significant increase also was observed in the content of alkali-soluble proteins in the spinal ganglia.
Key Wordsspace flight spinal cord spinal ganglia water-soluble proteins
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