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Bulletin of Experimental Biology and Medicine

, Volume 84, Issue 2, pp 1119–1121 | Cite as

Effect of space flight on composition of soluble proteins of the spinal cord and spinal ganglia of rats

  • A. V. Gorbunova
  • V. V. Portugalov
Biochemistry and Biophysics
  • 13 Downloads

Abstract

The content of individual protein fractions extracted from the spinal cord, at the level of the lumbar enlargement, and the spinal ganglia of rats consecutively with distilled water, 0.85% NaCl solution, and 0.1 N NaOH solution was investigated. A significant decrease in the content of water-soluble proteins was found in the white and gray matter of the spinal cord 12 h after space flight. The content of salt-soluble and alkali-soluble proteins in the structures of the spinal cord and spinal ganglia per milligram wet weight of tissue was not significantly altered. A significant increase in the content of water-soluble proteins compared with the control was found in the gray matter of the spinal cord 25 days after space flight. The content of water-soluble proteins in the white matter of the spinal cord was increased to the control level. A significant increase also was observed in the content of alkali-soluble proteins in the spinal ganglia.

Key Words

space flight spinal cord spinal ganglia water-soluble proteins 

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • A. V. Gorbunova
  • V. V. Portugalov
    • 1
  1. 1.Academy of Medical Sciences of the USSRUSSR

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