Abstract
The content of nuclear DNA in the epithelium of the endometrial glands of six healthy women of childbearing age and 10 women with menopausal dyshormonal glandular-cystic hyperplasia was investigated microspectrophotometrically. The DNA content in the normal uterine mucosa in the various phases of the menstrual cycle was unchanged, but in dyshormonal hyperplasia of the endometrium the DNA content was almost twice the normal value; a moderate increase in polyploidy also was observed.
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Literature Cited
G. G. Avtandilov, Yu. I. Blagoveshchenskii, A. S. Dalmatov, et al., Arkh. Patol., No. 10, 70 (1970).
G. G. Avtandilov, in: Problems in the Pathological Anatomy of Pretumor Processes (Proceedings of the Seventh Plenum of the Council of the All-Union Scientific Society of, Pathological Anatomists) [in Russian], Krasnodar (1973), pp. 23–27.
I. A. Kazantseva, “Mitotic regime concentration of sulfhydryl groups, and DNA content during hyperplasia and malignant transformation of certain human epithelial tissues,” Doctoral Dissertation, Moscow (1974).
G. I. Koreneva, Akush. Gin., No. 5, 72 (1962).
É. A. Lugovoi, “The endometrium in various phases of the menstrual cycle in glandular hyperplasia and in carcinoma of the body of the uterus,” Candidate's Dissertation, Krasnodar (1974).
P. I. Ponomareva, Vopr Okhr. Mat., No. 1, 74 (1969).
R. N. Stepanova, “The DNA content and mitotic activity of endometrial cells of women in the menstrual cycle,” Candidate's Dissertation, Dushanbe (1975).
Ya. E. Khesin, Dimensions of the Nuclei and the Functional State of Cells [in Russian], Moscow (1967).
E. Johannisson and K. Hagenbeldt, Acta Endocrinol. (Copenhagen),67, Suppl. 153, 81 (1971).
D. Pinero and G. Foraker, Am. J. Obstet. Gynec.,89, 657 (1964).
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Avtandilov, G.G., Treshcheva, N.D. DNA content in epithelial nuclei of endometrial glands in menopausal dyshormonal hyperplasias. Bull Exp Biol Med 83, 909–911 (1977). https://doi.org/10.1007/BF00798914
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DOI: https://doi.org/10.1007/BF00798914