Brain nucleic acid content of inbred rats of various strains
- 11 Downloads
Changes in the nucleic acid content were studied during defensive conditioning to electric shocks. In WAG rats a reflex was formed on average after 42.7 presentations of combined electrical and photic stimulation, compared with 14.09 combinations in August rats. Cytophotometric determination of the nucleic acid content in the neurons and perineuronal glia of the cortex revealed an increase in RNA only in August rats. It is suggested that the increased RNA synthesis in the animals of this strain may be the material basis of their greater ability to learn.
Key wordsinbred animals defensive conditioning nucleic acids neurons
Unable to display preview. Download preview PDF.
- 1.Yu. Ya. Geinisman, Structural and Metabolic Manifestations of Neuron Function [in Russian], Moscow (1974).Google Scholar
- 2.Yu. Ya. Geinisman, V. N. Larina, E. V. Maksimov, et al., Dokl. Akad. Nauk SSSR,202 1225 (1972).Google Scholar
- 3.L. Z. Pevzner, Dokl. Akad. Nauk SSSR,156, 1213 (1964).Google Scholar
- 4.L. Z. Pevzner, Tsitologiya, No. 9, 840 (1967).Google Scholar
- 5.D. Bovet, F. Bovet-Nitti, and A. Oliverio Science,163, 139 (1969).Google Scholar
- 6.R. D. Ciarnello, R. Barchas, S. Kessler, et al., Life Sci.,11, 565 (1972).Google Scholar
- 7.Z. Cohen, Physiol. Rev.,53, 373 (1973).Google Scholar
- 8.H. Hyden, Proc. Nat. Acad. Sci. USA,52, 1415 (1964).Google Scholar
- 9.J. Jarlsted Acta Physiol Scand.,67, 243 (1967).Google Scholar
- 10.J. Marx, Science,178, 1188 (1972).Google Scholar
- 11.D. McAfee, Science,171, 1156 (1971).Google Scholar