Abstract
An autoradiographic analysis was made of the dynamics of synthesis of nuclear and cytoplasmic RNA by sympathetic neurons of presenile mice subjected to partial desympathization during the first days after birth by injection of guanethidine. Neurons from a population with a sharply reduced number of cells have lower rates of migration of newly synthesized RNA from nucleus into cytoplasm than in the corresponding age control. Neurons of partially desympathized animals of infantile, juvenile, and presenile ages are no larger than the cell bodies of control mice.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
T. L. Dubina and A. N. Razumovich, Introduction to Experimental Gerontology [in Russian], Minsk (1975).
V. N. Yarygin and A. S. Pylaev, Byull. Éksp. Biol. Med., No. 6, 105 (1975).
V. N. Yarygin, P. P. Doronin, I. M. Rodionov, et al., Tsitologiya, No. 7, 800 (1976).
V. N. Yarygin, P. P. Doronin, I. M. Rodionov, et al., Tsitologiya, No. 8, 937 (1976).
K. N. Yarygiu, P. P. Doronin, I. M. Rodionov, et al., Tsitologiya, No. 8, 944 (1976).
K. N. Yarygin, “Cytological analysis of the population of growing sympathetic neurons,” Author's Abstract of Candidate's Dissertation, Moscow (1974).
Rights and permissions
About this article
Cite this article
Lebedev, D.B. Autoradiographic analysis of RNA synthesis by sympathetic neurons in a population containing a reduced number of cells. Bull Exp Biol Med 83, 890–892 (1977). https://doi.org/10.1007/BF00798908
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00798908